Antidiabetic components ofCassia alataleaves: Identification through α-glucosidase inhibition studies
نویسندگان
چکیده
منابع مشابه
Development of an antidiabetic formulation (ADJ6) and its inhibitory activity against α-amylase and α-glucosidase
There has recently been much advancement in the diagnosis, treatment, and research of metabolic disorders, especially diabetes. Current research around the world is focused on finding an alternative source of treatment from natural resources for diabetic management, apart from the available synthetic medicines. The present study is a preliminary study of a polyherbal formulation using edible na...
متن کاملAntioxidant, α-glucosidase inhibitory activity and sub-chronic toxicity of Derris reticulata extract: its antidiabetic potential
BACKGROUND Antidiabetic activity of Derris reticulata extract on alloxan-induced diabetic rats has been reported. The extract was found to lower blood glucose and inhibit intestinal glucose absorption. The aim of this study was to further investigate mechanisms underlying the antihyperglycemic activity of D. reticulata extract in vitro. METHODS The aqueous extract was obtained from D. reticul...
متن کاملQSAR Studies on Andrographolide Derivatives as α-Glucosidase Inhibitors
Andrographolide derivatives were shown to inhibit alpha-glucosidase. To investigate the relationship between activities and structures of andrographolide derivatives, a training set was chosen from 25 andrographolide derivatives by the principal component analysis (PCA) method, and a quantitative structure-activity relationship (QSAR) was established by 2D and 3D QSAR methods. The cross-validat...
متن کاملStudies on Antidiabetic Activity of Indian Medicinal Plants Using -Amylase and -Glucosidase Inhibitory Activity - A Pathway to Antidiabetic Drugs
Diabetes mellitus is a multifactorial disease. The nature has a plentiful sources as a remeady for this slow-killing condition. The aim of the present to assess the medicinal plants for anti-diabetic activity by using -amylase and -glucosidase inhibition assay. Anti-diabeticactivities of medicinal plants weredetermined by -amylase and -glucosidase inhibition assay. Results revealed that methono...
متن کاملInhibition of α-glucosidase, α-amylase, and aldose reductase by potato polyphenolic compounds
Diabetes mellitus is a chronic disease that is becoming a serious global health problem. Diabetes has been considered to be one of the major risks of cataract and retinopathy. Synthetic and natural product inhibitors of carbohydrate degrading enzymes are able to reduce type 2 diabetes and its complications. For a long time, potatoes have been portrayed as unhealthy for diabetic patients by some...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Pharmaceutical Biology
سال: 2012
ISSN: 1388-0209,1744-5116
DOI: 10.3109/13880209.2012.729066